Madecassol Centella Asiatica 1% Gotu Kola Extract Cicatrisant Cream Pomade 40 Grams,Scar Removal Skin Renewal

Product Information

The above studies with extracts from the same plant highlight the potential of our extract for further applications, since it mounts many different actions, making it more efficient at lower concentrations. Wound healing activity of extracts and formulations of Aloe vera, henna, Adiantum capillus-veneris, and myrrh on mouse dermal fibroblast cells. The stages involved in the healing process are hemostasis, inflammation, cellular proliferation, and tissue remodeling.

There are quite a few reports dealing with the wound healing potential of various plants, which in many cases was attributed to their antioxidant and antimicrobial properties, while reports on the wound healing properties of plants, not attributed, only, to such properties are scanty and sparse [ 6, 7, 8, 9]. As can be seen in Figure 2C(A–E), the addition of the extract increased the cell migration rate of HEK-293 and HaCaT cells, compared to control cells, after 24 h ( p< 0.Incorporating Madecassol cream into your skincare routine can help improve the health and appearance of your facial skin. Owing to the Soxhlet step that precedes the main extraction step, the as-prepared aqueous extract differs from previously reported aqueous extracts of Urtica dioica L.

Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues. Compared to other reports, the effect of our extract on the cell cycle is either similar or better [ 29, 30]. However, such a mechanism of action is only applicable to the first stages of wound healing, where there are plenty of free radicals [ 1]. For the identification of specific groups of phytochemicals in the extract, qualitative screening experiments were performed.Fibroblast proliferation and migration in wound healing by phytochemicals: Evidence for a novel synergic outcome. Alternatively, equivolume amounts of plant extract solution and Benedict’s reagent were mixed and placed in a boiling water bath for 5 min.

Centella Asiatica, ενός φυτού που ευδοκιμεί κυρίως στη νήσο Μαδαγασκάρη, έχει την ικανότητα να διεγείρει τη βιοσύνθεση του κολλαγόνου μέσα από τους ινοβλάστες του δέρματος και, ως εκ τούτου, τείνει να βοηθά στο μηχανισμό της επούλωσης. The viability of HEK-293 cells treated with the extract was increased compared to that of the untreated cells (control) after 24 h of incubation ( Figure 2A). Moreover, few fibroblasts are observed, and maturation begins at the deeper sites, while re-epithelization begins in the periphery.

At days 2 and 4, the area of the wound treated with Madecassol was reduced by 6 ± 1% and 14 ± 2%, respectively, while the area of the wound treated with 2 mg g −1 of the extract was reduced by 23 ± 1. In fact, it can even be paired with many potentially-irritating actives due to its soothing effects, notes Obioha. The supernatant was rejected, and the resulting cell pellet was washed with PBS, and centrifuged to the above conditions. Photographs were taken at a 5× magnification using a microcamera with an inverted phase microscope (Olympus CK40) (Olympus Optical Co. The electron donor ability is reported to be the main mechanism of the antioxidant activity of phenolic compounds [ 43].