It's Skin Collagen Voluming Toner

Product Information

Formulyst’s Pro-Collagen Serum contains a highly concentrated mix of peptides and proteins, as well as hydrating hyaluronic acid formulated for aging skin. Apply a few drops of this hydrating serum to help skin look smoother and younger. The most common animal collagen sources are human collagen, bovine, porcine, and marine organisms such as fish [ 24]. Despite the risk of bovine spongiform encephalopathy (BSE), bovine collagen is widely used in collagen-based products. The immune response to bovine collagen has been studied. A clinical study of 705 patients treated with a bovine collagen implant and a small percentage of patients had both the cellular and humoral types of the immune response [ 25]. Keefe, et al. showed that side effects to bovine collagen implants occurred in a small percentage of treated patients and these adverse reactions were resolved as the implant was resorbed by the patients [ 26]. Angiotensin-I converting enzyme (ACE) plays a key role in elevating blood pressure, and therefore, effective ACE inhibition can reduce blood pressure [ 27]. Bovine collagen is a promising precursor of ACE-inhibitory peptides in silico and in vitro protein digestions [ 28, 29]. The porcine collagen is widely used for extracting collagen as the bovine collagen. Porcine collagen does not cause much allergic response because it is almost similar to human collagen. Collagen peptides are promising for osteoporosis treatment and prevention. Porcine collagen peptides could be used to treat and prevent osteoporosis [ 30]. Porcine collagen membrane was tested in vitro and in vivo studies for guided bone regeneration [ 31]. The result indicated that the use of the porcine collagen membranes did not cause foreign body reactions and the porcine collagen membranes were biocompatible.

As you age, sustaining collagen levels becomes more difficult. This is particularly true for women who have already gone through menopause. This is because, over time, your body increasingly struggles to absorb adequate amounts of the nutrients needed to make collagen. Vitamin C is crucial for collagen synthesis, so you should also be sure to eat foods rich in this vitamin, such as citrus fruits, broccoli, and bell peppers ( 2, 4). DEAR MAYO CLINIC:I've read that collagen and biotin are good for the body. What are these supplements, and are they beneficial? Researchers have suggested that supplemental collagen may promote the synthesis of muscle proteins such as creatine, as well as stimulate muscle growth after exercise ( NEW15).From a general health perspective, it is important to ensure adequate protein within your diet. As you age, your protein needs increase slightly to maintain lean body mass. Consuming foods that contain the primary amino acids that make up collagen may help support skin, hair, nail and joint health as you age. Retinol is the main skincare ingredient that is thought to help promote collagen production. As Dr. Aivaz told Cedars-Sinai, “topical treatments like retinol and tretinoin are scientifically proven to promote collagen formation.” A 2006 paper in Clinical Interventions in Aging cites several studies noting this. As the authors noted, “ … Bhawan and colleagues (1995) evaluated the changes occurring at the dermal level in Caucasian skin after daily application of 0.05% tretinoin cream for a period of 12 months… However, after 12 months, formation of new collagen fibers as well as reduction in nodularly degenerated microfibrillar material was observed in the tretinoin-treated group.”

Bone mineral density tests measure bone strength and are used to help diagnose people with osteoporosis. A decreasing bone mineral density level can lead to an increased risk of bone fracture or worse bone breaks. These new proteins may not contain the same amino acids that were initially ingested in the collagen supplement, and it is unknown if these restructured proteins will target the area a supplement manufacturer is advertising. Therefore, it is undetermined at this time if the body will use a collagen supplement that is purported to help skin, hair, nail and joint support to actually make collagen that would do so. In addition, limited large and long-term randomized control trials support the use and recommendation for collagen supplements for the general public. Gingival recession (GR) is the exposure of root surfaces that is caused by apical migration of the gingival tissue margins and is frequently detected in adults [ 96]. The reference therapy for GR is the connective tissue graft (CTG) plus coronally advanced flap (CAF). Collagen bioscaffold was used for the treatment of GR [ 97]. For GR, cell adhesion in the scaffold influences the integration, migration, and survival of the cells among the scaffold. Collagen was found to be a superior bioscaffold for the treatment in GR. In a prospective randomized, controlled 18 adult patients clinical trial, a porcine collagen matrix plus CAF treatment showed no statistically significant differences compared with the CTG plus CAF treatment evaluated at 12 months [ 98]. As a result, the collagen matrix could be a possible alternative to CTG. Moreover, due to aging or disease, dentinal collagen undergoes glucose-related crosslinking. However, it remains unknown how collagen crosslinking affects the early adhesion of related oral streptococci. Schuh et al. studied the effect of glycated collagen on oral streptococcal nanoadhesion to help develop a new preventive and therapeutic treatment against dental caries [ 99].Collagen supplements are generally considered safe and are associated with few negative side effects when used as directed. Asserin et al. investigated the efficacy of oral collagen peptide supplementation on skin hydration in a clinical study [ 49]. After several weeks of intake, the oral collagen peptide supplementation remarkably increased skin hydration, the collagen density in the dermis remarkably increased and the fragmentation of the dermal collagen network remarkably decreased. These effects persevered after 12 weeks. The results suggested that oral collagen peptide supplementation significantly improved skin aging. However, several vegan-friendly collagen-boosting supplements are already on the market. These usually contain ingredients that support collagen production, such as vitamin C. However, eating collagen-rich foods can help your body overcome some of this absorption problem. As a result, your body can stay stronger and healthier even as you get older. As we get older, our bodies don’t produce as much collagen. By some estimates, skin loses 1% of its collagen every year starting in the mid-thirties and then it nose dives. The dermatologist Dr. Ohara Aivaz told Cedars-Sinai’s blog that “ For women, we can lose up to 30% of our collagen production in the first 5 years of menopause.”