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Tossex Antitussive Cough Syrup is a combination medicine used in the treatment of dry cough. It relieves allergy symptoms such as runny nose, stuffy nose, throat irritation, sneezing, watery eyes and congestion or stuffiness. Calafat AM, Wong LY, Kuklenyik Z, Reidy JA, Needham LL. Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003–4 and comparisons with NHANES 1999-2000. Environ Health Perspect. 2007;115: 1596–602. Sun Q, Li X, Li A, Zhang J, Ding Z, Gong H, et al. Ventral hippocampal-prefrontal interaction affects social behavior via parvalbumin positive neurons in the medial prefrontal cortex. iScience. 2020;23:100894.Vollmer LL, Schmeltzer S, Schurdak J, Ahlbrand R, Rush J, Dolgas CM, et al. Neuropeptide Y impairs retrieval of extinguished fear and modulates excitability of neurons in the infralimbic prefrontal cortex. J Neurosci. 2016;36:1306–15. Bourgeois JP, Goldman-Rakic PS, Rakic P. Synaptogenesis in the prefrontal cortex of rhesus monkeys. Cereb Cortex. 1994;4:78–96. Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, et al. Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis. Nat Neurosci. 2018;21:1117–25. R Core Team. R: A Language and Environment for Statistical Computing; R Foundation for Statistical Computing: Vienna, Austria, 2017. Bereczki E, Francis PT, Howlett D, Pereira JB, Höglund K, Bogstedt A, et al. Synaptic proteins predict cognitive decline in Alzheimer’s disease and Lewy body dementia. Alzheimer’s Dement: J Alzheimer’s Assoc. 2016;12:1149–58.

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Browning D The Ever-Increasing Hazards of the Household. TIME: New York 2012 Available from http://ideas.time.com/2012/05/31/the-ever-increasing-hazards-of-the-household/ (Accessed 8 June 2018). Gulsuner S, Walsh T, Watts AC, Lee MK, Thornton AM, Casadei S, et al. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013;154:518–29. Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, et al. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nat Commun. 2018;9:2459. Yuen EY, Liu W, Karatsoreos IN, Ren Y, Feng J, McEwen BS, et al. Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory. Mol Psychiatry. 2011;16:156–70. As expected, living in a city with a PFAS-contaminated water supply was associated with higher serum concentrations of PFAS chemicals. We found a significant association with three of the six PFAS chemicals evaluated (PFOA, PFNA, and PFHxS). Despite the potential for UCMR3 data to misclassify some participants—for example, those served by a small water supply not monitored under UCMR3 or by a private well, or who live in a city served by multiple public water supplies—the positive associations that we observed are consistent with findings from Hurley et al. [ 14] and emphasize that contaminated drinking water can be a substantial contributor to PFAS exposure. Having stain-resistant treated furniture and carpets were associated with higher levels of PFNA in all participants and PFDeA in non-Hispanic whites. Treated furniture and carpets are known sources of PFASs including PFNA and PFDeA [ 31], although previous studies of exposure have detected links with sulfonic, rather than carboxylic, PFASs [ 13, 52].