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Complex polysaccharides derived from natural sources such as pectins and galactomannans, pH- and heat-modified pectins (for example, MCPs), and galactomannan-derived compounds have shown antitumoural, antimetastatic and anti-inflammatory activities 138, 211, 212, 213, 214. S. Conti, et al., “Modified Citrus Pectin as a Potential Sensitizer for Radiotherapy in Prostate Cancer,” Integr. Cancer Ther. 17(4), 1225–1234 (2018). Galectin-3fuels chronic inflammation andits progressionin the body. It alsoaids tumour growth, metastasis and angiogenesis (new blood vessels thatsupply the tumour).
Galectins dampen antitumour immune responses by targeting both lymphoid and myeloid cells 38 (Fig. 2). Notably, galectin–glycan interactions alter the immune landscape in several cancer types 112, 113, 114, 115, 116, 117, 118. Moreover, galectins modulate cancer-associated fibroblasts and can influence their pro-tumorigenic and pro-metastatic activities 119. Galectin-3 is a carbohydrate-binding protein made in the body anda key cancer marker. It is known to be involved in cancer parthenogenesis. It is also atherapeutic target for drugs and has been extensively researched for its role in promoting cancer and chronic disease. In 2018, for example, clinical results from an ongoing multicentre trial on this form of MCP in biochemically relapsed prostate cancer were presented at the American Society for Clinical Oncology Genitourinary Conference. Reported in the Journal of Clinical Oncology, the study — “Effects of Pectasol-C Modified Citrus Pectin Treatment on PSA Dynamics in Non-Metastatic Biochemically Relapsed Prostate Cancer Patients” — demonstrated the ability of the only researched form of MCP to significantly slow PSA doubling time and halt disease progression in the majority of subjects. 1 What is galectin-3 (Gal-3)?These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease. PectaSol® Metal Detox provides clinically proven, natural detoxification to helplower body burden of heavy metals and environmental toxins such as radioactive particles. PectaSol® Metal Detox combines the detoxification properties of PectaSol-C® Modified Citrus Pectin and Algimate®, modified alginates purified from kelp seaweed, to bind to heavy metals in the digestive and circulation systems without disrupting essential mineral balance, for safe elimination.* In a 2011 study, MCP was shown to be a potent immune system booster. It had a powerful effect boosting B-lymphocytes, and also the cytoxic effects of T-lymphocytes and Natural Killer (NK) cells against cancer. MCP actually produced a dramatic 10-fold increase in NK cell activity (7) . Classifying this myriad of conditions — from arthritis to zoster pain — that we now understand to be instigated and advanced by this culprit biomarker, is critical in advancing the application of Gal-3 as both a prognostic indicator and key therapeutic target.
Pectin isa soluble fibre, which cannot be absorbed into the body. Apolysaccharide, the body cannot break it down into its constituent molecules. Typically, it is found in the cell wall of plants, vegetables and fruits - like apples, carrots and in the peel of citrus fruit and plums. BEST PRICES GUARANTEED on over 2.6 million Hotels Worldwide. Instant confirmation. Book now - pay when you stay. 24/7 customer service. Villas, Apartments B&B too. Save a further 10% with Genius. Swindle PW, Kattan MW, Scardino PT. Swindle PW, et al. Urol Clin North Am. 2003 May;30(2):377-401. doi: 10.1016/s0094-0143(02)00176-3. Urol Clin North Am. 2003. PMID: 12735513 Review. Published in 2006, a study demonstrated PectaSol-C MCP's ability to bind and remove toxic heavy metals from the body, without affecting essential minerals. Heavy metal removal with PectaSol-C MCP has been shown in multiple case studies to play a role in ongoing body maintenance.From driving proinflammatory, profibrotic and procancerous pathways to promoting immune evasion, metabolic dysfunction and blood-brain barrier permeability, Gal-3 plays such a fundamental role that some experts are calling for a new category of health conditions: Elevated Galectin-3 Diseases. What’s more, MCP also lowered the rate of acute kidney injury, which went from 89% in the control group to 44% in both groups taking the modified pectin [ 14]. Improving Cognition Other Ingredients: Vegetable capsule (natural vegetable cellulose, water), vegetable stearic acid, magnesium stearate, microcrystalline cellulose, silicon dioxide. Extracellular Gal-3 acts as an adhesion surface protein, forming lattices with itself, binding glycoproteins and glycolipid membrane receptors and creating a gel-like biofilm that anchors other procancerous growth factors and inflammatory compounds within the extracellular matrix.
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