abb-entrelec XLP1 – 6BC – desconectador Fuse 3 Poles

Product Information

In many cases, XLP1 is an inherited condition, meaning it is passed on in families in the same way that physical characteristics, such as eye colour, are passed from parent to child. It is caused by a mutation (change) in a child’s genetic make-up. Specialists in genetics and genetic counselling are on hand to talk through the inheritance of XLP1 with you if needed, and PID UK has a separate information leaflet devoted to the genetics of primary immunodeficiency. lymphoproliferation excessive numbers of lymphocytes, causing enlarged lymph nodes, liver and spleen, and sometimes affecting other organs.

Please make sure all customers are aware of the suspension and freight is held until advised further. The aim is to give enough treatment to control the overactive lymphocytes without losing protection against infection, while avoiding other side effects. Some people affected by XLP1 are more likely to develop infections than normal and may benefit from regular (prophylactic) antibiotics and immunoglobulin replacement. ‘Live’ vaccines should be avoided. In many cases, an inactive form of a vaccine is available.A variety of other symptoms have been reported. These include bone marrow failure, causing anaemia and vasculitis. macrophage a type of cell that engulfs and digests microbes, damaged or dead cells. They also take part in the anti-inflammatory response to decrease immune reactions. McDowell Ltd 2023. All rights reserved. Registered in England No: 02348762. Registered office: Thunderbird Depot, Valley Road, Keighley, West Yorkshire, BD21 4LZ

haematopoietic stem cell transplant (HSCT) the transfer of stem cells from a donor – either related or unrelated – to a recipient. Stem cells may be obtained from bone marrow (from the hip bone – this is also known as bone marrow transplantation), peripheral blood (PBSCs), or from stored umbilical cord blood. Haematopoietic means blood-forming. The donor cells are given by intravenous infusion and make their way to the recipient bone marrow to provide a new immune system, curing the immunodeficiency. immunoglobulin replacement therapy administration of immunoglobulin purified from plasma to people with immune deficiency. The immunoglobulin contains antibodies that help protect against infection. This treatment can be given through a vein or under the skin. white blood cells (leucocytes) a group of small, colourless blood cells that play a major role in the body’s immune system. There are five basic types of white blood cells: monocytes, lymphocytes, neutrophils, eosinophils and basophils.Natural Killer (NK) cells a type of lymphocyte particularly important in fighting viral infections and protecting against cancer.