Becodefence, Plus Nasal Spray – Gets to Work in 3 Minutes NonDrowsy 120 Sprays, 20 ml

Product Information

The usual dose is 1 to 2 sprays into each nostril once per day. Follow your doctor's dosing instructions very carefully. The use of beclometasone dipropionate should be avoided during pregnancy unless thought essential by the doctor.

Steroid medicine can weaken (suppress) your immune system, and you may get an infection more easily. If you use this medicine long-term, you may need frequent medical tests. Following an oral dose, B-17-MP is absorbed slowly with peak plasma levels reached 3-5 hours after dosing.

With mometasone nasal spray, very little medicine is absorbed into the rest of your body, so it's not likely to give you serious side effects.# The recommended dosage is two sprays into each nostril twice daily (400 micrograms/day). Once control has been established it may be possible to maintain control with fewer sprays. A dosage regimen of one spray into each nostril morning and evening has been shown to be efficacious in some patients. However, should symptoms recur, patients should revert to the recommended dosage of two sprays into each nostril morning and evening. The minimum dose should be used at which effective control of symptoms is maintained. Total daily administration should not normally exceed eight sprays. If you have beclometasone nasal spray on prescription, your doctor will tell you how often to use the nasal spray and when to change your dose. How to use it Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor or pharmacist. Georgitis JW, Meltzer EO, Kaliner M, Weiler J, Berkowitz R. Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge. Ann Allergy Asthma Immunol 2000;84(4):451-459.

BDP is cleared very rapidly from the circulation and plasma concentrations are undetectable (< 50pg/ml) following oral or intranasal dosing. There is rapid metabolism of the majority of the swallowed portion of BDP during its first passage through the liver. The main product of metabolism is the active metabolite (B-17-MP). Minor inactive metabolites, beclometasone-21-monopropionate (B-21-MP) and beclometasone (BOH), are also formed but these contribute little to systemic exposure. There is inadequate evidence of safety in human pregnancy. Administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate and intra-uterine growth retardation. There may therefore be a very small risk of such effects in the human foetus. It should be noted, however, that the foetal changes in animals occur after relatively high systemic exposure. Beconase Aqueous Nasal Spray delivers beclometasone dipropionate directly to the nasal mucosa and so minimises systemic exposure. If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. What if I use too much? Following intranasal administration of BDP in healthy males, the systemic absorption was assessed by measuring the plasma concentrations of its active metabolite B-17-MP, for which the absolute bioavailability following intranasal administration is 44% (95% CI 28%, 70%). After intranasal administration, <1% of the dose is absorbed by the nasal mucosa. The remainder after being cleared from the nose, either by drainage or mucocilary clearance, is available for absorption from the gastrointestinal tract. Plasma B-17-MP is almost entirely due to conversion of BDP absorbed from the swallowed dose.Bend your head forward slightly and carefully put the nozzle into your other nostril keeping the bottle upright. If you're using high doses of beclometasone, or you're using it alongside other steroid medicines or tablets for HIV, you may get underactive adrenal glands. Your doctor may recommend that you carry a red steroid emergency card. This card is the size of a credit card and fits in your wallet or purse. If you're using a new bottle, it may not work first time. Pump the spray a few times until a fine mist comes out. You'll also need to do this if the bottle has not been used for a few days. Beclometasone nasal spray takes a few days to work fully. For some people it can take 2 weeks or more to get the maximum benefits. Beclometasone nasal (nose) spray is used to treat cold-like symptoms caused by allergic rhinitis. This is swelling (inflammation) of the inside of your nose that can be brought on by allergies like hay fever.