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Gonge G-2117 Tactile Discs, Multicolour

£41.495£82.99Clearance
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Smith KR Jr (1970) The ultrastructure of the human Haarscheibe and Merkel cell. J Invest Dermatol 54:150–159 DURABLE PLASTIC DISCS: As well as being strong enough to be grabbed and stepped on, they offer long-lasting durability for home and classroom use. With non-slip pads on the bottom of each plate, even on smooth surfaces, there is no need to worry about children falling over.

Ikeda R, Cha M, Ling J, Jia Z, Coyle D, Gu JG (2014) Merkel cells transduce and encode tactile stimuli to drive Abeta-afferent impulses. Cell 157:664–675 Maricich SM, Wellnitz SA, Nelson AM, Lesniak DR, Gerling GJ et al (2009) Merkel cells are essential for light-touch responses. Science 324:1580–1582 Hires SA, Efros AL, Svoboda K (2013) Whisker dynamics underlying tactile exploration. J Neurosci 33:9576–9591

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Tachibana T, Nawa T (2002) Recent progress in studies on Merkel cell biology. Anat Sci Int 77:26–33 Munger BL (1965) The intraepidermal innervation of the snout skin of the opossum. A light and electron microscope study, with observations on the nature of Merkel’s Tastzellen. J Cell Biol 26:79–97 Gottschaldt KM, Vahle-Hinz C (1981) Merkel cell receptors: structure and transducer function. Science 214:183–186 Mills LR, Diamond J (1995) Merkel cells are not the mechanosensory transducers in the touch dome of the rat. J Neurocytol 24:117–134 PORTABLE SENSORY EXPERIENCE: A portable sensory tactile experience that may ease anxiety and stress. Each disc features a different texture that can calm the body and mind creating moments of mindfulness throughout the day at school, at-home, or on-the-go!

Albers J, Chaudhry V, Cavaletti G, Donehower R (2007) Interventions for preventing neuropathy caused by cisplatin and related compounds. Cochrane Database Syst Rev 24:CD005228

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A mechanoreceptor is a sensory receptor that responds to mechanical pressure or distortion. For instance, in the periodontal ligament, there are mechanoreceptors that allow the jaw to relax when biting down on hard objects; the mesencephalic nucleus is responsible for this reflex. Chalfie M, Au M (1989) Genetic control of differentiation of the Caenorhabditis elegans touch receptor neurons. Science 243:1027–1033 Ikeda I, Yamashita Y, Ono T, Ogawa H (1994) Selective phototoxic destruction of rat Merkel cells abolishes responses of slowly adapting type I mechanoreceptor units. J Physiol 479(Pt 2):247–256

Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y et al (2013) Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature 493:221–225 Ebara S, Kumamoto K, Matsuura T, Mazurkiewicz JE, Rice FL (2002) Similarities and differences in the innervation of mystacial vibrissal follicle-sinus complexes in the rat and cat: a confocal microscopic study. J Comp Neurol 449:103–119Diamond J, Holmes M, Nurse CA (1986) Are Merkel cell-neurite reciprocal synapses involved in the initiation of tactile responses in salamander skin? J Physiol 376:101–120

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