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Opium for Women by Yves Saint Laurent Eau de Toilette Spray 50ml

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Under the Federal Controlled Substances Act opium poppy and poppy straw are listed as Schedule II drugs under ACSN 9630. Most (all?) states also use this classification under the uniform penal code. Possession of a Schedule II drug is a federal and state felony. As the textile industry developed in Britain during the Industrial Revolution, the EIC drove Indian farmers out of cotton cultivation and shutting down Indian weaving operations. [15] :7 The EIC encouraged farmers to cultivate opium instead, over time resulting in opium crops far in excess of the demand for medicinal use. [15] :7

Opium contains 50 different alkaloid opiates. The most common metabolism of opiates is to be ultimately converted to morphine which is further converted to morphine-3,6-diglucuronide. 16 Opioids are metabolized vastly by the enzyme CYP 2D6 and any mutation in this kind of enzyme or coadministration with drugs that interfere with this enzyme may generate a change in the metabolism speed. 18 For years, because of this metabolism pathway, it was very hard to differentiate between illicit heroin users and involuntary exposure to poppy seeds. The original tests for this differentiations were based in the presence of morphine in urine without evidence of 6-monoacetylmorphine. Now it is known the presence of a glucuronide metabolite only in the consumption of heroin called ATM4G and this allows a clear differentiation of the consumption of illegal heroin and poppy seed ingestion. 6

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Hanes, W. Travis; Sanello, Frank (2002). Opium Wars: The Addiction of One Empire and the Corruption of Another. Sourcebooks. ISBN 9781402201493. . popular history.

Burma bans cultivation in certain provinces. In northern Burma bans have ended a century-old tradition of growing the opium poppy. Between 20,000 and 30,000 former poppy farmers left the Kokang region as a result of the ban in 2002. [56] People from the Wa region, where the ban was implemented in 2005, fled to areas where growing opium is still possible.Opium produces its effects by activating specific G protein-coupled receptors in the brain, spinal cord, and peripheral nervous system. There are three major classes of opioid receptors being δ-opioid, κ-opioid and μ-opioid. Opium will generate an agonist activity which will later open the potassium channels and prevent the opening of voltage-gated calcium channels. This activity causes a reduction in neuronal excitability and inhibits the release of pain neurotransmitters. 9 a b D., Kapoor, L. (1995). Opium poppy: botany, chemistry, and pharmacology. New York: Food Products Press. ISBN 978-1560249238. OCLC 30544395. {{ cite book}}: CS1 maint: multiple names: authors list ( link) Layton, Thomas N. (1997). The Voyage of the 'Frolic': New England Merchants and the Opium Trade. Stanford University Press. ISBN 9780804729093. Fairbank, John King. Trade and Diplomacy on the China Coast: The Opening of the treaty ports, 1842-1854 (Cambridge, Harvard U. P, 1953) online. Opium smoking began only after the early Europeans in North America discovered the Indian practice of smoking tobacco in pipes. Some smokers began to mix opium with tobacco in their pipes, and smoking gradually became the preferred method of taking opium. Opium smoking was introduced into China from Java in the 17th century and spread rapidly. The Chinese authorities reacted by prohibiting the sale of opium, but these edicts were largely ignored. During the 18th century European traders found in China an expanding and profitable market for the drug, and the opium trade enabled them to acquire Chinese goods such as silk and tea without having to spend precious gold and silver. Opium addiction became widespread in China, and the Chinese government’s attempts to prohibit the import of opium from British-ruled India brought it into direct conflict with the British government. As a result of their defeat in the Opium Wars, the Chinese were compelled to legalize the importation of opium in 1858. Opium addiction remained a problem in Chinese society until the Communists came to power in 1949 and eradicated the practice.

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