Emetrol Nausea and Upset Stomach Relief Liquid Medication, Cherry - 4 oz Bottle

Product Information

Emetrol is rapidly absorbed after oral administration, with peak plasma concentrations occurring at approximately 1hr after dosing. The Cmax and AUC values of Emetrol increased proportionately with dose in the 10mg to 20mg dose range. A 2- to 3-fold accumulation of Emetrol AUC was observed with repeated four times daily (every 5 hr) dosing of Emetrol for 4 days. Urinary and faecal excretions amount to 31 and 66% of the oral dose respectively. The proportion of the drug excreted unchanged is small (10% of faecal excretion and approximately 1% of urinary excretion). The plasma half-life after a single oral dose is 7-9 hours in healthy subjects but is prolonged in patients with severe renal insufficiency.

Emetrol suspension contains 400mg of liquid sorbitol (non-crystallising, E420) per ml, which may have a mild laxative effect. Patients with rare hereditary problems of fructose intolerance should not take this medicine.Although Emetrol's bioavailability is enhanced in normal subjects when taken after a meal, patients with gastro-intestinal complaints should take Emetrol 15 - 30 minutes before a meal. Reduced gastric acidity impairs the absorption of Emetrol. Oral bioavailability is decreased by prior concomitant administration of cimetidine and sodium bicarbonate. Treatment with Emetrol should be stopped if signs or symptoms occur that may be associated with cardiac arrhythmia, and the patients should consult their physician. Emetrol Oral Suspension is contraindicated in moderate or severe hepatic impairment. Dose modification in mild hepatic impairment is however not needed. Although neurological side effects are rare , the risk of neurological side effects is higher in young children since metabolic functions and the blood-brain barrier are not fully developed in the first months of life. Overdosing may cause extrapyramidal symptoms in children, but other causes should be taken into consideration.

If you are allergic to Emetrol (fructose, dextrose, and phosphoric acid); any part of Emetrol (fructose, dextrose, and phosphoric acid); or any other drugs, foods, or substances. Tell your doctor about the allergy and

Pregnancy & Lactation

The dose of medicine can now be swallowed directly from the oral syringe. Please ensure that you are sitting upright and the plunger must be pushed slowly to allow you to swallow the dose. Emetrol Oral Suspension should be used at the lowest effective dose for the shortest duration necessary to control nausea and vomiting.