Alka-Seltzer Effervescent Gold - 36 Tablets, Pack of 2

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Increased haematological toxicity of methotrexate (decreased renal clearance of methotrexate by anti-inflammatory agents in general and displacement of methotrexate from its plasma protein binding by salicylates).

Disturbances of the gut such as nausea, vomiting, diarrhoea or abdominal pain. This can be helped by taking Alka-Seltzer with or after food. Temperature also affects the rate of a reaction. When temperature is increased, molecules move faster, so it is likely there will be more collisions in the same amount of time. Think about a class of students entering a room. If they walk, there is less chance that they will bump into another student, but if all the students are running into the room it is very likely there will be some collisions between students. In your trials, did the hot or cold water finish first? From your observations in Part 2, how did the temperature change affect how fast the reaction occurred? Though its name suggests an issue with one's heart, heartburn is actually a symptom of acid reflux − the burning sensation of acid refluxing up from one's stomach and into the esophagus. While several conditions contribute to heartburn, one of its most commonly recommended treatments is Alka-Seltzer − an antacid known for "decreasing the amount of acid in the stomach," says Lisa Young, an adjunct professor of nutrition at New York University and author of "Finally Full, Finally Slim." What is Alka-Seltzer?

Alka-Seltzer original should not be taken by breastfeeding mothers because aspirin passes into breast milk and may be harmful to the nursing infant. Ask your pharmacist for advice on what medicines you can take if you're breastfeeding. Due to its inhibitory effect on platelet aggregation which persists for several days after administration, acetylsalicylic acid may lead to an increased bleeding tendency during and after surgical operations (including minor surgeries, e.g. dental extractions). Heartburn is one of the most common ailments people deal with regularly. According to a National Institutes of Health report, about 60 million Americans experience heartburn at least once a month, while some 15 million feel some measure of it daily. Alka-Seltzer reacts with an acid to make carbon dioxide gas. When you added the tablet to the vinegar or water, you heard fizzing and saw bubbling. If the reaction is going faster, then it will take less time to finish and will fizz more vigorously. Inhibition of prostaglandin synthesis may adversely affect the pregnancy and/or the embryo/foetal development. Data from epidemiological studies suggest an increased risk of miscarriage and of cardiac malformation and gastroschisis after use of a prostaglandin synthesis inhibitor in early pregnancy. The absolute risk for cardiovascular malformation was increased from less than 1%, up to approximately 1.5 %. The risk is believed to increase with dose and duration of therapy. In animals, administration of a prostaglandin synthesis inhibitor has been shown to result in increased pre- and post-implantation loss and embryo-foetal lethality. In addition, increased incidences of various malformations, including cardiovascular, have been reported in animals given a prostaglandin synthesis inhibitor during the organogenetic period. During the first and second trimester of pregnancy, acetylsalicylic acid should not be given unless clearly necessary. If acetylsalicylic acid is used by a woman attempting to conceive, or during the first and second trimester of pregnancy, the dose should be kept as low and duration of treatment as short as possible.

As you start the stopwatch, slide the Alka-Seltzer tablet pieces down the crease of the paper into the second cup of vinegar.The listed adverse drug reactions are based on spontaneous reports, thus an organization according to CIOMS III categories of frequency is not possible. Tell all of your health care providers that you take Alka-Seltzer (aspirin, citric acid, and sodium bicarbonate). This includes your doctors, nurses, pharmacists, and dentists. As you start the stopwatch, slide the powdered Alka-Seltzer down the crease of the paper into the third cup of vinegar.

People with an active peptic ulcer, perforation (hole) or bleeding in the gut, or a history of these problems. Do not take Alka-Seltzer (aspirin, citric acid, and sodium bicarbonate) for longer than you were told by your doctor. Disposal: All liquids and solutions can be poured down the drain with running water. Solid waste can be disposed of in the trash. Introduction of activity possible prolongation of bleeding time, an anti-aggregating effect which may occur even at very low doses. Related/similar drugs acetaminophen, ibuprofen, omeprazole, famotidine, amitriptyline, naproxen, diclofenac What are some things I need to know or do while I take Alka-Seltzer?Generic name: Aspirin, Citric Acid, and Sodium Bicarbonate [ AS-pir-in-SIT-rik-AS-id-& SOW-dee-um-bye-KAR-bun-ate]