N / C 100 5ml needleless plastic syringes, can be used multiple times, suitable for scientific laboratory, metering, watering, adding water, refueling

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Download PDF Info Publication number USRE43824E1 USRE43824E1 US13/077,571 US200213077571A USRE43824E US RE43824 E1 USRE43824 E1 US RE43824E1 US 200213077571 A US200213077571 A US 200213077571A US RE43824 E USRE43824 E US RE43824E Authority US United States Prior art keywords gas particles nozzle syringe convergence Prior art date 2001-01-11 Legal status (The legal status is an assumption and is not a legal conclusion. This species of bacteria is sometimes found in tap water, and had been previously associated with infections from jet injectors. the device is so constructed and arranged that substantial boundary layer separation between the wall of the nozzle and the gas jet is avoided thus enabling the particles accelerated out of the exit nozzle in the gas jet to be distributed across substantially the full width of the nozzle's downstream exit.

skin or mucosa) positioned in close proximity to the nozzle exit, the size of the target area impacted by the particles will be generally equal to the size of the bore 3 at the downstream exit of the nozzle 2 and the particles will be well distributed across the target area. Samir Mitragrotri visually captured splash-back after discharging a multi-use nozzle jet injector using high-speed microcinematography. Retrograde flow happens after the jet stream penetrates the skin and creates a hole, if the pressure of the jet stream causes the spray, after mixing with tissue fluids and blood, to rebound back out of the hole, against the incoming jet stream and back into the nozzle orifice. Sutermeister, a mechanical engineer, witnessed a worker injure his hand from a high-pressure jet stream and theorized of using the concept to administer medicine. By distributing the particles in the flow of gas from a needleless syringe using the method of the above first aspect of the present invention, whilst the nozzle's downstream exit is positioned adjacent a target area of skin or mucosa, the particles may be administered to the skin or mucosa.a large divergent portion 17 of the exit nozzle 2 can cause “coring” whereby the boundary layer separates from the nozzle walls and the majority of the jet power is concentrated along a central longitudinal axis such that the particles are not evenly distributed across the full area of the nozzle at the nozzle exit plane. the present invention is primarily concerned with the reduction of noise and improved uniform particle spread that can be achieved by using the Venturi effect to draw the particles into the gas flow path. the preferred gas for the gas source is helium, with the gas cylinder containing helium gas at a pressure of between 15 and 35 bar, preferably around 30 bar. the method and mechanism of operation of the fifth embodiment is similar to that of the first to fourth embodiments and will not be further described here. Marshall Lockhart, an engineer, filed a patent for his idea of a jet injector after learning of Sutermeister's invention.

penetration increases but the particle distribution becomes more skewed to that side of the target which is opposite the position of powder entry via the particle inlet passage 10 . the downstream parallel section 65 following the divergent section 17 helps to reattach the boundary layer which can become separated in the divergent section 17 and yields a more uniform particle distribution across the whole exit diameter of the nozzle. While this may sound like an easy and affordable way to get fillers, remember that it can lead to a serious injury. This sonic nozzle 4 is provided with an aperture which forms a first convergence or constriction 5 to the flow of gas through the main body 1 .mm, the good spread of the particles across a target area substantially equal to the area of the nozzle bore 3 at the nozzle exit 2 will be appreciated. Because, however, of the large variation of the saturation pressure of CO 2 with temperature, and the much lower velocities achievable therewith, the use of CO 2 may be limited. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed. A jet injector, also known as a jet gun injector, air gun, or pneumatic injector, is a medical instrument that uses a high-pressure jet of liquid medication to penetrate the skin and deliver medication under the skin without a needle. The needleless syringe can also be used in conjunction with surgery to deliver drugs and biologics to organ surfaces, solid tumours and/or to surgical cavities (e.

Although penetration depth has again fallen slightly (to 140 ⁇ m), the powder was still found to be substantially uniformly distributed over the full target area, the target area of course this time having a diameter of approximately 14 mm. the main body 30 is provided with a nozzle 31 having an upstream parallel-sided section 32 , a short divergent section 33 downstream thereof, followed by a long downstream generally conical section 34 . the mass flow rate of gas through the device is determined by the driver pressure and the smallest cross sectional flow area in the device. the main body 1 of the syringe has a central aperture extending therethrough to form a lumen which bounds the gas flow path through the syringe, into the downstream end of which is fitted a nozzle 2.the main body 1 of the syringe has a central aperture extending therethrough to form a lumen which bounds the gas flow path through the syringe, into the downstream end of which is fitted a nozzle 2 .

A single- shot button canister 61 comprising a plunger 64 and a sleeve body 62 defining a gas reservoir space 63 is shown attached to the FIG. a gas source is necessary to pressurize the central aperture of the main body 1 upstream of the sonic nozzle 4 (ie. comprises an elongate tubular converging-diverging nozzle having a rupturable membrane initially closing the passage through the nozzle and arranged substantially adjacent to the upstream end of the nozzle. The US Department of Veterans Affairs recognized for the first time that a veteran acquired Hepatitis C from his military jet injections and awarded service-connection for his disability. Examples of suitable surfactants include, for example, Tergitol® and Triton® surfactants (Union Carbide Chemicals and Plastics, Danbury, Conn.JAK inhibitors are helping patients with alopecia areata, eczema/atopic dermatitis, psoriasis, and vitiligo. When the cassette is engaged in a recess provided in the exterior side wall of the main body 1, for example to form an interference fit therewith, a hole in the cassette provided at the base of the reservoir 12 lines up in communication with the particle inlet passage 10. mg payload of 55 μm lidocaine powder, the syringe was able to deliver the payload in such a way as to consistently anaesthetise a 2 to 3 mm diameter of the forearm within one minute. The Department of the Army made multi-use nozzle jet injectors the standard for administering immunizations.