Herbal Magic's Pure & Natural Blend - Biotin Powder (10,000 mcg in 1 Scoop) - UKAS LAB Tested in UK - Made from 14 x Fruits, Vegetables & Herbs - No fillers/Preservatives/Color/Maltodextrin-Pack of 1

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Includes a variety of protein foods such as lean meats; poultry; eggs; seafood; beans, peas, and lentils; nuts and seeds; and soy products. Boccaletti V, Zendri E, Giordano G, Gnetti L, De Panfilis G. Familial Uncombable Hair Syndrome: Ultrastructural Hair Study and Response to Biotin. Pediatr Dermatol 2007;24:E14-6. [ PubMed abstract] Biotin, a B vitamin, is an essential nutrient that is naturally present in some foods and available as a dietary supplement. This water-soluble vitamin is a cofactor for five carboxylases (propionyl-CoA carboxylase, pyruvate carboxylase, methylcrotonyl-CoA carboxylase [MCC], acetyl-CoA carboxylase 1, and acetyl-CoA carboxylase 2) that catalyze critical steps in the metabolism of fatty acids, glucose, and amino acids [ 1-5]. Biotin also plays key roles in histone modifications, gene regulation (by modifying the activity of transcription factors), and cell signaling [ 3].

Keep in mind that there’s little evidence to support the use of biotin for hair, nail, or skin health. Consuming a healthy, well-rounded diet will do much more for your hair, skin, and nails than taking a supplement.Kury S, Ramaekers V, Bezieau S, Wolf B. Clinical utility gene card for: Biotinidase deficiency-update 2015. Eur J Hum Genet 2016;24. [ PubMed abstract] This is a fact sheet intended for health professionals. For a general overview of Biotin, see our consumer fact sheet on Biotin. Introduction Li D, Radulescu A, Shrestha RT, Root M, Karger AB, Killeen AA, et al. Association of biotin ingestion with performance of hormone and nonhormone assays in healthy adults. JAMA 2017;318:1150-60. [ PubMed abstract] Hill MJ. Intestinal flora and endogenous vitamin synthesis. Eur J Cancer Prev 1997;6:S43-5. View abstract.

Eakin RE, Snell EE, and Williams RJ. Concentrationand assay of avidin, injury-producing agents in raw egg white. J Biol Chem. 1941;(40):535-43. Piketty ML, Prie D, Sedel F, et al. High-dose biotin therapy leading to false biochemical endocrine profiles: validation of a simple method to overcome biotin interference. Clin Chem Lab Med 2017;55(6):817-25. View abstract.

Top 5 Biotin Supplements

So don’t assume taking biotin supplements will cure hair, skin or nail problems. “If you notice sudden changes in your hair, skin or nails, see your provider,” says Barth. “Don’t self-treat with biotin supplements without knowing the cause.” How much biotin do you need? Floersheim GL. [Treatment of brittle fingernails with biotin]. Z Hautkr 1989;64:41-8. [ PubMed abstract] If you’re planning on taking biotin supplements for hair loss or beard thinning, seek medical advice first to try and identify the root cause of the problem.

Biotin contributes to maintenance of normal hair and skinBiotin supports normal psycological function Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: https://books.nap.edu/books/0309065542/html/.

Is biotin safe to take every day?

While there have been a few small studies conducted which show a positive impact of taking the supplement, these have not shown results that are firmly conclusive. What are the potential benefits of taking biotin? Krause KH, Kochen W, Berlit P, Bonjour JP. Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy. Int J Vitam Nutr Res 1984;54:217-22. View abstract. Ozand, P. T., Gascon, G. G., Al Essa, M., Joshi, S., Al Jishi, E., Bakheet, S., Al Watban, J., Al Kawi, M. Z., and Dabbagh, O. Biotin-responsive basal ganglia disease: a novel entity. Brain 1998;121 ( Pt 7):1267-1279. View abstract. The FNB found the available data to be insufficient to derive an EAR and RDA for biotin. For this reason, the FNB established only AIs for biotin. The FNB based its determination of AIs for all populations on the amount of biotin in human milk consumed by infants and then used body weight to extrapolate AIs for other groups [ 11]. Table 1 lists the current AIs for biotin [ 1]. Table 1: Adequate Intakes (AIs) for Biotin [ 1] Age