BRITA MAXTRA+ replacement water filter cartridges, compatible with all BRITA jugs -reduce chlorine, limescale and impurities for great taste - 3 pack

Product Information

In rats, the oral LD 50 is 680 ug/kg and the subcutaneous LD 50 is 1630 ug/kg. In mice, the oral LD 50 is 4700 ug/kg, the intraperitoneal LD 50 is 48 mg/kg, and the subcutaneous LD 50 is 34 mg/kg. Maxtra binds to α 1- and α 2-adrenoceptors, which are Gq-protein-coupled receptors that promote vascular smooth muscle contraction by increasing intracellular calcium levels in response to ligand activation. Maxtra Syrup 60 ml contains Chlorpheniramine and Phenylephrine. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant that narrows the small blood vessels, relieving the nose's congestion or stuffiness. Together, Maxtra Syrup 60 ml effectively reduces allergic symptoms.

It is important that you must discuss about your medical history in general whenever you consult a doctor. Ask your doctor whether you are fit to consume this medication or not as the medication can affect the functioning of kidney in some cases, especially if you are already suffering from kidney related issues. Following single-drop ocular administration of oxymetazoline in healthy adult subjects, the mean ± SD C max was 30.5 ± 12.7 pg/mL and the area under the concentration-time curve (AUC inf) was 468 ± 214 pg x hr/mL. The median T max was 2 hours, ranging from 0.5 to 12 hours.This medicine provide temporary relief of nasal congestion and eustachian tube congestion along with the associated symptoms. Maxtra Syrupmay cause drowsiness. Avoid driving or operating machinery while taking this medication. Maxtra Syrup is primarily prescribed to treat common cold. This is a combination syrup that has Chlorpheniramine and Phenylephrine as active ingredients. It also relieves the associated symptoms such as runny nose, itching of the throat and nose, watery eyes, and sneezing due to upper respiratory infections. Ans : This syrup should be used on the basis of severity of symptoms or as consulted by the doctor. There are some advised dose for the children of 2 to 6 years of age is 2.5 - 5 ml every hours and 5 - 10 ml every hour for the children above 6 years of age. And all the doses should be given in a proper measured manner with a measuring cup. For the best results it should be given at evenly spaced intervals. Maxtra Syrup 60 ml contains a combination of two different drugs. Chlorpheniramine being a class B pregnancy drug and phenylephrine being a class C. So, it should be used with caution Phenylephrine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

You should avoid driving whenever possible if you are under this medication. It may cause drowsiness or dizziness in some cases, which can affect your driving skills. Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert. Ans : It is an antihistamine which restricts the action of histamine and work as a reliever from the symptoms such as Sinus pressure, Sinus congestion, Running nose, Throat itching, Hay fever, Allergies, sneezing because of respiratory infections, Watering eyes, Cough. It is advisable that you do not consume the syrup if you are pregnant or expecting to be pregnant soon. There is no sufficient information to call it safe for consumption during such conditions.It is not habit-forming in most case but it can get addictive for some. You may consult a doctor if you are experiencing signs of addictiveness. Chlorphenamine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from: The syrup does interact with certain medicines or ingredients that can result in negative implications. If you are under medications or supplements that have ingredients or drugs like alcohol, antipsychotics, digoxin, decongestants, phenytoin, sedatives or tricyclic antidepressants. You must consult a doctor to get a better understanding on how to go about the dosages or look for substitutes in such conditions. Maxtra is an adrenergic α1- and α2-agonist and a direct-acting sympathomimetic drug. By stimulating adrenergic receptors, oxymetazoline causes vasoconstriction of dilated arterioles and reduces blood flow. In a radioligand competition study, oxymetazoline displayed higher affinity at α1A-adrenoceptors compared to α2B-adrenoceptors, but with higher potency at α2B-adrenoceptors. When sprayed intranasally, oxymetazoline relieved relief nasal congestion and improved nasal airflow in patients with acute coryzal rhinitis for up to 12 hours following a single dose.