Nuromol Pain Relief Tablets, Paracetamol and Ibuprofen, Pack Of 16, From The Makers Of Nurofen

Product Information

People taking any other painkillers containing paracetamol or ibuprofen, or any other NSAID painkillers, including COX-2 inhibitors such as celecoxib. If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist If one tablet does not relieve your symptoms, you can take a maximum of two tablets up to three times a day. Do not take more than two tablets together and no more than six tablets in 24 hours. In patients with severe hepatic failure, severe renal failure or severe heart failure (NYHA Class IV) (see Section 4.4). If ibuprofen is used in combination with quinolone antibiotics, such as ciprofloxacin or norfloxacin there may be an increased risk of seizures (fits). This may occur in people with or without a previous history of epilepsy or convulsions.

Nuromol Dual Action Pain Relief 200/500mg Tablets | Nurofen

include agranulocytosis, anaemia, aplastic anaemia, haemolytic anaemia leucopenia, neutropenia, pancytopenia and thrombocytopenia. The toxicological safety profile of ibuprofen and paracetamol has been established in animal experiments and in humans from extensive clinical experience. There are no new preclinical data of relevance to the prescriber which are additional to the data already presented in this Summary of Product Characteristics. Are allergic to ibuprofen, paracetamol or any other ingredient of the product, aspirin or other related painkillers. Serious skin reactions have been reported in association with Nuromol treatment. You should stop taking Nuromol and seek medical attention immediately, if you develop any skin rash, lesions of the mucous membranes, blisters or other signs of allergy since this can be the first signs of a very serious skin reaction. See section 4

The patient should consult a doctor if the symptoms persist or worsen or if the product is required for more than 3 days. The antipyretic effect is reported to be linked to the effect on the prostanoid synthesis due to the fact that the prostanoids are the main signaling mediator of pyresis in the hypothalamic-preoptic region. Paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center). Ibuprofen also brings down a fever by reducing the production of prostaglandins in the brain. How do I take Nuromol? Do not take with any other paracetamol containing products. Immediate medical advice should be sought if this occurs, even if you feel well as this can result in an overdose (see section 4.9).

Nuromol Pain Relief Tablets, Paracetamol and Ibuprofen, Pack Nuromol Pain Relief Tablets, Paracetamol and Ibuprofen, Pack

Paracetamol's exact mechanism of action is still not completely defined; however, there is considerable evidence to support the hypothesis of a central antinociceptive effect. Various biochemical studies point to inhibition of central COX-2 activity. Paracetamol may also stimulate the activity of descending 5-hydroxytryptamine (serotonin) pathways that inhibit nociceptive signal transmission in the spinal cord. Evidence has shown that paracetamol is a very weak inhibitor of peripheral COX-1 and 2 isoenzymes. if you experience: • heartburn, indigestion • signs of intestinal bleeding (severe stomach pain, vomiting blood or liquid with what looks like coffee mg per kg body weight daily in divided doses. In children weighing less than 30 kg the total daily dosage should not exceed 500 mg. If gastrointestinal disturbances occur Ibuprofenshould be given with food or milk. a) Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes. The other Nuromol Ingredients include: croscarmellose sodium, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, stearic acid.As an independent pharmacy, My Pharmacy is able to get the best prices for both generic and brand name treatments. When compared to other retailers such as Asda, Nuromol Boots, Sainsbury’s, My Pharmacy can be as much as 50% cheaper to buy the same products. Nuromol UK

Nurofen Plus vs Nuromol: What is the difference? - Versus Nurofen Plus vs Nuromol: What is the difference? - Versus

Experimental data suggest that ibuprofen may competitively inhibit the effect of low dose acetylsalicylic acid on platelet aggregation when they are dosed concomitantly. Some pharmacodynamic studies show that when single doses of ibuprofen 400 mg was taken within 8 h before or within 30 min after immediate release acetylsalicylic acid dosing (81 mg), a decreased effect of acetylsalicylic acid on the formation of thromboxane or platelet aggregation occurred. Although there are uncertainties regarding extrapolation of these data to the clinical situation, the possibility that regular, long-term use of ibuprofen may reduce the cardioprotective effect of low-dose acetylsalicylic acid cannot be excluded. No clinically relevant effect is considered to be likely for occasional ibuprofen use (see section 4.5).When GI bleeding or ulceration occurs in patients receiving ibuprofen containing products, the treatment should be withdrawn.