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Currenttranslational research partnerships ongoingwith AstonUniversity in collaboration with life sciences for early and exploratorydevelopment of new drugs to modulate cardiac fibrosis (grant applicationsin process) Member ofCouncil, Royal College ofPhysicians of Edinburgh (2015-) and has acted as West MidlandsRegional Adviser for the RCPE (2013-). October 2016: SWBH ‘Trust Beacon Service award’ for Cardiology, as ‘an internationally-recognised centre for atrial fibrillation’, and SWBH ‘Excellence in Research’ award for my Atrial Fibrillation research team, which topped the SWBH league table in 2015-16 in terms of numbers of patients recruited to research studies on the NIHR portfolio, as well as major contributions to the delivery of the Trust’s R&D plan including enhanced integration with primary care and the translation of research into better and safer clinical care. Diabetes - defined as current use of insulin or anti-diabetic drugs, or a fasting glycemia >125mg/dL (7mmol/L). It usually goes with high values of hemoglobin A1c. Directed Letter - Local overseas Allowance, overseas private vehicle provision policy from 1 April 2021 (including all Annexes)After reading the letter I approached my Admin Office who read the regulations differently, and are not willing to cough up, although they do agree that they are ambiguous and are seeking clarification.

Professor Lip has ledvarious 'real world' registries, as well ashealth economicanalyses and outcomes researchindependently or industry-sponsored(see PMID: 26316345;PMID: 26477648).Some have been used to inform NICE cost-effectiveness models and appraisals, allowingthe NHS and public sector to make informeddecisions with efficient use of resources.

Validity

Potpara TS, Lip GYH, Blomstrom-Lundqvist C, et al. The 4S-AF scheme (stroke risk; symptoms; severity of burden; substrate): a novel approach to in-depth characterization (rather than classification) of atrial fibrillation. Thromb Haemost 2021;121:270–8. In terms of OAC therapy, the mean TTR was lower in those non-adherent to the ABC pathway compared to ABC-adherent patients (59.4%±22.3% vs. 63.9%±21.1%; p=0.002), and among those non-adherent to the ABC pathway at baseline, a higher proportion presented with a TTR <65% than TTR ≥65% (56.4% vs. 43.6%, p=0.023). In addition, 144 (21.9%) patients adherent to the ABC pathway switched to a DOAC during the follow-up, and 67 (17.3%) non-adherent patients did so ( p=0.195). Clinical Outcomes During the Follow-up Both employees and self-employed workers will pay less in National Insurance from next year, Chancellor Jeremy Hunt has announced in today's Autumn Statement. In this prospective cohort study including real-world AF patients, we found that patients adherent to the ABC pathway at baseline had a significantly lower risk of net clinical outcomes, all-cause mortality, and cardiovascular death.

AF has major clinical implications on patients’ quality of life, morbidity with ischaemic stroke and heart failure, and mortality when compared with the general population. 1 AF is the most common sustained arrhythmia and it has been calculated that it will affect 17.9 million adults in the EU and the UK by 2060. 2 The increasing prevalence of AF is driven mainly by the ageing population and the high burden of risk factors and comorbidities, which raises significant issues about the use of healthcare systems and economic costs. 2–4

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Martin Lewis: What the Autumn Statement means for you – including wages, benefits, pensions, ISAs, national insurance and more Pastori D, Pignatelli P, Menichelli D, Violi F, Lip GYH. Integrated Care Management of Patients With Atrial Fibrillation and Risk of Cardiovascular Events: The ABC (Atrial fibrillation Better Care) Pathway in the ATHERO-AF Study Cohort. Mayo Clin Proc. 2019;94(7):1261-7. Hypertension - defined as a blood pressure measurement >140/90mmHg on two separate occasions, or current antihypertensive treatment. The management of atrial fibrillation (AF) has evolved during the last decade. The search for a more comprehensive, integrated, and holistic management of AF patients had led to the proposal of the Atrial fibrillation Better Care (ABC) pathway 1. This simple strategy, which aims to streamline primary and secondary care of patients with AF, is based on three pillars: “A” avoid stroke; “B” better symptom control; and “C” cardiovascular risk factor and other comorbidities management 1. Roldán V, Martínez-Montesinos L, López-Gálvez R, García-Tomás L, Lip GYH, Rivera-Caravaca JM, et al. Relation of the 'Atrial Fibrillation Better Care (ABC) Pathway' to the Quality of Anticoagulation in Atrial Fibrillation Patients Taking Vitamin K Antagonists. J Pers Med. 2022;12(3).

Added: Directed Letter: Continuity of education allowance (CEA) - regulatory flexibility in response to coronavirus (COVID-19) - (including Annex A and B and Appendix 1 to Annex B) and deleted 2 out of date documents. Overall clinical research work into AF has also had a major impact on recommendations in AF guidelines issued by NICE (2006 and 2014), as well as the ESC (2010, 2012 and 2016), CCS (2011) and ACCP (2012). Professor Lip's research has informed European consensus guidelines on the optimal management of anticoagulated AF patients who present with an acute coronary syndrome ± undergo coronary intervention/stenting (ESC, 2010 and 2014), as well as the assessment/management of bleeding in AF patients (European Heart Rhythm Association (EHRA), 2011). June 2015,delivered the Opening Ceremony Plenary Lecture at theNorwegian Cardiac Society meeting, Tromso, Norway

Study

Editor in Chief (Clinical Studies) [2010-] of ‘Thrombosis & Haemostasis’ (2016 Impact factor 5.627). There are seven significant stroke risk factors in the CHA2DS2-Vasc scale. The name of the scale is an acronym of the risks. All are worth an either 0 or 1 point, except age, which can be worth 2, and stroke, which is only worth 0 or 2. October 2016: Prof.Chudomir Nachev Lecture, at the 15th Bulgarian National Congress of Cardiology, Sofia, Bulgaria January 2015, delivered the Sun Chieh Yeh Heart Foundation Lecture at the Opening Ceremony of the Cardiorhythm 2015 meeting in Hong Kong. Professor Lip is a Board member of the European Heart Rhythm Association (EHRA) and is Chairman of its Scientific Documents Committee (2013-).